Frequency of LTP (Pru p 3) and Profilin (Pru p 4) sensitisation in 1052 patients referenced to an immunoallergology department in Lisbon
نویسندگان
چکیده
Background Lipid transfer proteins (LTP) and profilins are the most relevant panallergens in the clinical management of patients with allergy to pollen and plant food (mainly fresh fruits and tree nuts) in the Mediterranean countries. Knowledge of the prevalence of sensitization to these allergens in the population would be useful in clinical practice. In this study we analyze the frequency of LTP and profilin sensitization in patients referred to the outpatient clinic in Lisbon.
منابع مشابه
Frequency of LTP (Pru p 3) and profilin (Pru p 4) sensitization in 1052 patients referenced to an Imunoallergology Department in Lisbon
Background Lipid Transfer Proteins (LTP) and profilins are the most important panallergens in the clinical management of patients with allergy to pollen and plant food (mainly tree nuts and fresh fruits) in the Mediterranean countries. Knowledge of the prevalence of sensitization to these allergens in the population would be extremely useful. In this study we analyze the frequency of sensitizat...
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Rosaceae fruit allergy is the most common food allergy in Europe in patients over 5 years of age. The two fruits most frequently involved are peach and apple. Different clinical phenotypes of peach allergy are observed across Europe in relation to different allergen sensitisation patterns to the peach allergens Pru p1 (Bet v 1 homologue), Pru p 3 (peach lipid transfer protein, LTP), and Pru p 4...
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In the Mediterranean area, lipid transfer proteins (LTPs) are important causes of plant-food allergies often associated with severe allergic reactions. There, peach LTP (Pru p 3) seems to be the primary sensitizer, whereas in Central Europe, little is known about the importance of LTP sensitization. In this region, allergen extract-based diagnosis is often complicated by co-sensitization to Bet...
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BACKGROUND In Italy, the nsLTP (Pru p 3) has been identified as the most frequent cause of food allergy and anaphylaxis. In order to estimate the risk assessment in peach allergy, we investigated the presence of correlations between the levels of sIgE to Pru p 3 with the severity of the clinical symptoms in two Pru p 3 positive populations from two different areas of Italy. METHODS 133 consec...
متن کاملDo Skin Prick Test and In Vitro Techniques Diagnose Sensitization to Peach Lipid Transfer Protein and Profilin Equally Well in Allergy to Plant Food and Pollen?
OBJECTIVE To compare the skin prick test (SPT) with in vitro techniques (single and multiplex fluorescence enzyme-immunoassay [FEIA]) for detecting sensitization to profilin and lipid transfer protein (LTP). METHODS We retrospectively studied 181 patients with pollen and/or plant food allergy and 61 controls. SPT was performed with date palm profilin (Pho d 2) and peach LTP (Pru p 3), and spe...
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